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Apexbio Technology LLC N-Acetylserotonin 1210-83-9 250mg
Supplier: Apexbio Technology LLC C5386250
N-Acetylserotonin (CAS 1210-83-9) is a biochemical intermediate in the melatonin biosynthetic pathway formed via acetylation of serotonin by arylalkylamine N-acetyltransferase (AANAT) It acts as an agonist at melatonin receptors MT1 MT2 and MT3 which are G protein-coupled receptors involved in circadian regulation Distinctively N-acetylserotonin rapidly activates the TrkB receptor in vitro and in vivo in a circadian fashion independently of neurotrophins and the MT3 receptor This TrkB activation has been associated with antidepressant-like effects in animal models N-Acetylserotonin is thus valuable for research on neurotrophic signaling circadian biology and the molecular mechanisms underlying mood regulation
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