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Medchemexpress LLC N-(Amino-PEG1)-N-bis(PEG2-propargyl) | 2100306-47-4 | 98.0% | 356.46 | 25 MG
Supplier: Medchemexpress LLC 25MGHY140086
N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is a click chemistry reagent, containing an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Azide groups
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
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