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Apexbio Technology LLC N-Arachidonylglycine 179113-91-8 100mg

Supplier: Apexbio Technology LLC B6742100
N-Arachidonylglycine (NA-Gly CAS 179113-91-8) is an endogenous lipid molecule structurally related to the endocannabinoid anandamide NA-Gly functions as a selective agonist of the G protein-coupled receptor GPR18 exhibiting an EC50 of approximately 44 5 nM while showing negligible affinity for classical cannabinoid receptors CB1 and CB2 Additionally NA-Gly acts as an inhibitor of the glycine transporter GLYT2 with an IC50 of around 5 1 M Experimental studies have demonstrated that NA-Gly promotes migration of endometrial cells indicating its applicability in investigations of lipid signaling pain modulation and cellular migration mechanisms
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