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Cayman Chemical N-desmethyl GalntamIn 10mg
Supplier: Cayman Chemical 3507410 MG
An alkaloid and active metabolite of galantamine; inhibits AChE (IC50 = 0.23 µM) and ACh-induced currents by 64.8% in Xenopus oocytes expressing human α7 nAChRs at 100 µM; is cytotoxic to MOLT-4 cells and LMTK alveolar fibroblasts (IC50s = 0.6 and 0.5 UG/ml, respectively); decreases disease severity in a mouse model of carbon tetrachloride-induced acute liver injury at 1 and 10 mg/kg
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