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Medchemexpress LLC N-Fmoc-8-aminooctanoic acid | 126631-93-4 | 98.95% | 381.46 | 10 G
Supplier: Medchemexpress LLC HYW00903010G
N-Fmoc-8-aminooctanoic acid functions as a PROTAC linker in the synthesis of PROTACs. It consists of an alkane chain featuring terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic conditions to yield a free amine, suitable for subsequent conjugations. Additionally, the terminal carboxylic acid can react with primary amine groups in the presence of activators like EDC or HATU to form a stable amide bond.
- Used as a PROTAC linker in the synthesis of PROTACs.
- Comprises an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups.
- Fmoc group is deprotectable under basic conditions to obtain a free amine for further conjugations.
- Terminal carboxylic acid can react with primary amine groups with activators to form a stable amide bond.
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