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Medchemexpress LLC N,N-bis(1,3-benzodioxol-5-ylmethyl)-1-butyl-2,4-diphenyl-1H-imidazole-5-methanamin | 439571-48-9 | 99.4% | 573.68 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY11006010MG

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NDT 9513727 is a potent, selective, orally active, and competitive inverse agonist of the human C5aR (C5a receptor), with an IC50 of 11.6 nM. It can be used for the research of human inflammatory diseases.

  • Potent and selective inverse agonist of human C5aR.
  • Orally active and competitive.
  • Inhibits C5a-stimulated responses such as Ca2+ mobilization, oxidative burst, and chemotaxis.
  • Exhibits dose-dependent inhibition of hC5a-induced neutropenia.
  • Moderate oral bioavailability and plasma elimination half-lives.

Catalog No. 50-003-44345


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