Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Apexbio Technology LLC N1-Methylpseudo-UTP (sodium salt) 50ul (100 mM)
Supplier: Apexbio Technology LLC B88000.05
N1-Methylpseudo-UTP (sodium salt) is a modified nucleotide analog utilized as a substrate for enzymatic in vitro transcription reactions aimed at generating messenger RNA (mRNA) molecules for biomedical research This nucleotide contains the N1-methylpseudouridine base modification which helps to reduce innate immune system activation triggered by exogenous mRNA transcripts within mammalian cells Incorporating N1-methylpseudo-UTP into synthetic transcripts decreases recognition by intracellular pattern-recognition receptors thereby lowering innate immune responses and enhancing cellular tolerance upon transfection Consequently N1-methylpseudo-UTP incorporation has been actively employed in developing mRNA constructs for therapeutic applications such as vaccine development protein replacement therapies and gene-editing platforms
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?