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Apexbio Technology LLC N1-Methylpseudo-UTP (sodium salt) 50ul (100 mM)
SDP

Supplier:  Apexbio Technology LLC B88000.05

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N1-Methylpseudo-UTP (sodium salt) is a modified nucleotide analog utilized as a substrate for enzymatic in vitro transcription reactions aimed at generating messenger RNA (mRNA) molecules for biomedical research This nucleotide contains the N1-methylpseudouridine base modification which helps to reduce innate immune system activation triggered by exogenous mRNA transcripts within mammalian cells Incorporating N1-methylpseudo-UTP into synthetic transcripts decreases recognition by intracellular pattern-recognition receptors thereby lowering innate immune responses and enhancing cellular tolerance upon transfection Consequently N1-methylpseudo-UTP incorporation has been actively employed in developing mRNA constructs for therapeutic applications such as vaccine development protein replacement therapies and gene-editing platforms

Catalog No. 50-000-62955


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