Apexbio Technology LLC Naftifine HCl 65473-14-5 500mg

Supplier:  Apexbio Technology LLC B1984500

Naftifine HCl (CAS 65473-14-5) is a small-molecule inhibitor targeting squalene 2 3-epoxidase It is designed to inhibit this key enzyme thereby disrupting the fungal sterol biosynthetic pathway Naftifine HCl exerts its biological activity primarily through inhibition of squalene 2 3-epoxidase leading to intracellular squalene accumulation and impairment of fungal membrane formation and integrity In in vitro studies Naftifine HCl demonstrates inhibitory activity with IC50 values generally ranging between 20 100 nM against common dermatophytes and fungal pathogens Based on these pharmacological properties Naftifine HCl holds research potential in studies of fungal infections and sterol synthesis inhibition mechanisms including conditions such as tinea pedis tinea corporis and tinea cruris

Catalog No. 50-000-93012