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Apexbio Technology LLC Naspm trihydrochloride 1049731-36-3 10mg
Supplier: Apexbio Technology LLC B718010
Naspm trihydrochloride (CAS 1049731-36-3) is a selective inhibitor of Ca sup 2 /sup -permeable AMPA receptors a subtype of glutamate-gated ion channels involved in mediating fast excitatory synaptic transmission in the central nervous system This compound preferentially antagonizes AMPA receptors lacking the GluR2 subunit such as GluR1 homomeric channels exhibiting an IC sub 50 /sub of 0 3 M By blocking these receptors Naspm trihydrochloride is widely used to elucidate the physiological roles of Ca sup 2 /sup -permeable AMPA receptors in synaptic plasticity neuronal signaling and excitotoxicity research
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