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Medchemexpress LLC Nbd-14270 | 2411819-82-2 | 99.5% | 425.43 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY139989100MG

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NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist. It binds to HIV-1 gp120 and shows potent antiviral activity.

  • Potent HIV-1 entry antagonist with an IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses.
  • Binds to HIV-1 gp120.
  • Low cytotoxicity (CC50>100 μM).
  • Anti-HIV-1 activity (IC50=0.16 μM) and Cytotoxicity (CC50=109.3 μM) in single-cycle (TZM-bl Cells) assay.
  • Does not induce toxicity in the U87-CD4-CXCR4 cell line at doses used for assay.

Catalog No. 50-003-51370


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