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Apexbio Technology LLC NECA 35920-39-9 10mg
Supplier: Apexbio Technology LLC B516410
NECA is a non-selective small-molecule agonist targeting adenosine receptors which are G-protein coupled receptors involved in immune modulation and inflammatory responses It is designed to activate these receptors thereby modulating downstream signaling pathways related to cytokine release and immune cell activation NECA exerts its biological activity primarily through adenosine receptor activation In experimental studies NECA has been employed to investigate receptor-mediated immune suppression in primary murine glial cells by reducing cytokines such as CXCL10 and TNF- Based on these pharmacological properties NECA holds research potential in immune regulation during Toxoplasma gondii infection modulation of Th1 and Th17 cell responses in autoimmune uveitis models and enhancing anticonvulsant drug penetration in epileptic animal models
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