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Medchemexpress LLC Necrocide 1 | 1247028-61-0 | MFCD12149407 | 98.8% | 365.47 | C23H27NO3 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY143075MG

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Necrocide 1 is a small-molecule research reagent that acts as a selective TRPM4 agonist to induce necrotic cell death by sodium overload (NECSO) and promote immunogenic cell death markers in cellular and in vivo cancer studies. It is characterized by submicromolar activity and high purity for experimental use.

  • Selective TRPM4 agonist with EC50 ≈ 306.3 nM.
  • Induces necrotic and immunogenic cell death (CALR exposure, ATP secretion, HMGB1 release).
  • Suitable for breast and prostate cancer research models.
  • High purity (98.84%) for reproducible experimental results.
  • Soluble in DMSO (100 mg/mL); established in vivo formulation protocols available.

Catalog No. 50-002-21697


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