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Medchemexpress LLC NecroIr2 | 99.0% | 926.44 | C46H30ClIrN6O2- | 10 MG
Supplier: Medchemexpress LLC HY14836610MG
NecroIr2 is an iridium(III) complex necroptosis inducer active in cisplatin-resistant lung cancer (A549R) cells. It selectively accumulates in mitochondria, triggers oxidative stress and loss of mitochondrial membrane potential, activates RIPK3 and MLKL, and modulates CDK4 expression. Intended for laboratory research use.
- Iridium(III) complex with mitochondrial accumulation.
- Induces necroptosis in cisplatin-resistant lung cancer cells.
- Activates RIPK3 and MLKL signaling pathways.
- Causes oxidative stress and loss of mitochondrial membrane potential.
- Supplied in multiple pack sizes and high purity for research applications.
- Store sealed away from moisture and light; use cold storage for solutions.
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