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Medchemexpress LLC Neoandrographolide | 27215-14-1 | 480.59 | 1 ML
SDP

Supplier:  Medchemexpress LLC HYN072110MM/1ML

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Neoandrographolide is a diterpenoid compound derived from Andrographis paniculata. It inhibits osteoclast differentiation and bone resorption by targeting the MAPK/NF-κB/PI3K/AKT/GSK3β/PPAR/CAMK signaling pathway. Additionally, it prevents apoptosis in rat embryonic ventricular cardiomyocytes, and demonstrates anti-inflammatory and hypolipidemic effects by suppressing inducible nitric oxide synthase (iNOS) and reactive oxygen species (ROS) generation, while simultaneously activating endothelial nitric oxide synthase (eNOS).

  • Inhibits osteoclast differentiation.
  • Alleviates bone resorption.
  • Inhibits apoptosis in rat embryonic ventricular cardiomyocytes.
  • Exhibits anti-inflammatory activity.
  • Shows hypolipidemic activity.

Catalog No. 50-004-16706


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