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Medchemexpress LLC Neriifolin | 466-07-9 | MFCD00869436 | 1 ML
Supplier: Medchemexpress LLC HYN844110MM/1ML
Neriifolin is a CNS-penetrating cardiac glycoside and an inhibitor of Na+, K+-ATPase. It targets beclin 1, which inhibits the formation of LC3-associated phagosomes and helps to ameliorate the development of experimental autoimmune encephalomyelitis (EAE). Additionally, Neriifolin can induce cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.
- Targets Atg8/LC3, Na+/K+ ATPase, Apoptosis, Beclin1
- Used in cardiovascular disease research
- Used in inflammation/immunology research
- Used in cancer research
- Inhibits the formation of LC3-associated phagosomes
- Ameliorates experimental autoimmune encephalomyelitis development
- Induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells
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