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Medchemexpress LLC Netarsudil | 1254032-66-0 | 99.94% | 25 MG
Supplier: Medchemexpress LLC 25MGHY12798
Netarsudil (AR-13324) is a competitive inhibitor of Rho-associated protein kinases (ROCK I and ROCK II) and a reversible inhibitor of the norepinephrine transporter (NET). It reduces intraocular pressure by inhibiting ROCK, which causes relaxation of trabecular meshwork cells and dilation of episcleral veins, thereby increasing aqueous humor outflow. It also inhibits NET to reduce aqueous humor production. Netarsudil is primarily used in the study of ocular hypertension and primary open-angle glaucoma.
- Reduces intraocular pressure by inhibiting ROCK.
- Increases aqueous humor outflow.
- Inhibits norepinephrine transporter (NET) to reduce aqueous humor production.
- Used in the study of ocular hypertension.
- Used in the study of primary open-angle glaucoma.
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