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CPC Scientific H-Ile-Leu-Gln-Arg-Gly-Ser-Gly-Thr-Ala-Ala-Val-Asp-Phe-Thr-Lys-Lys-Asp-His-Thr-Ala-Thr-Trp-Gly-Arg-Pro-Phe-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2 (trifluoroacetate salt) 0.5MG
Supplier: CPC Scientific NEUP007A
This peptide was originally isolated from rat brain as an endogenous ligand for two orphan G protein-coupled receptors FM-3/GPR66 and FM-4/TGR-1, which have been identified as neuromedin U (NMU) receptors. hNMS-33 is specifically expressed in the suprachiasmatic nuclei (SCN) of the hypothalamus. It has been shown that NMS is implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions.ONE-LETTER SEQUENCE: ILQRGSGTAAVDFTKKDHTATWGRPFFLFRPRN-NH2MOLECULAR FORMULA: C173H265N53O44MOLECULAR WEIGHT:3791.34STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [1138204-27-9], RESEARCH AREA: ObesityREFERENCES: K.Mori et al., EMBO J., 24, 325 (2005)
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