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ABclonal Technology Neuropilin-1 NRP1 Rabbit mAb
Supplier: ABclonal Technology A22213100UL
This gene encodes one of two neuropilins which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration Neuropilins contain a large N-terminal extracellular domain made up of complement-binding coagulation factor V VIII and meprin domains These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain Neuropilins bind many ligands and various types of co-receptors they affect cell survival migration and attraction Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells
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