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Medchemexpress LLC NF-κB/MAPK-IN-1 | 2413940-56-2 | 98.7% | 477.51 | 5 MG
Supplier: Medchemexpress LLC HY1479725MG
NF-κB/MAPK-IN-1 (compound 11a) is a potent inhibitor of NF-κB and MAPK pathway. It demonstrates inhibitory activity against NO production, with an IC50 of 6.96 μM. This compound suppresses LPS-induced iNOS, COX-2, ERK, and P38 signaling activation. NF-κB/MAPK-IN-1 can prevent LPS-induced inflammatory response in macrophages and is suitable for research on rheumatoid arthritis (RA).
- Potent inhibitor of NF-κB and MAPK pathway.
- Exhibits inhibitory activity against NO production with an IC50 of 6.96 μM.
- Suppresses LPS-induced iNOS, COX-2, ERK, and P38 signaling activation.
- Prevents LPS-induced inflammatory response in macrophages.
- Suitable for research on rheumatoid arthritis (RA).
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