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Medchemexpress LLC NHS-MMAF | 1404073-19-3 | 97.2% | C49H78N6O12 | 10MG

Supplier: Medchemexpress LLC HY13932610MG
NHS-MMAF is an N-hydroxysuccinimide-activated derivative of monomethyl auristatin F used as a payload intermediate for antibody-drug conjugate (ADC) synthesis. It acts as a tubulin polymerization inhibitor and is intended for research use in ADC linker and conjugation development; it is described in patent WO2012143499 (intermediate 219).
- NHS-activated ester for amine conjugation.
- Suitable for antibody-drug conjugate linker chemistry.
- High reported purity (97.2%).
- Solid, white to off-white appearance for easy handling.
- Soluble in DMSO for reaction setup.
- Serves as a payload precursor for cytotoxic conjugates.
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