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Medchemexpress LLC Nialamide | 51-12-7 | 96.3% | 100 MG
Supplier: Medchemexpress LLC HYB1199100MG
Nialamide is a non-selective monoamine oxidase (MAO) inhibitor that functions by inhibiting MAO and regulating reactive oxygen species (ROS) production. It can induce hyperkinesis in animals, enhance the anticonvulsant effect of Diphenylhydantoin in mice, increase rectal temperature, and enhance the pressor effect of Norepinephrine. This compound is suitable for research related to depression, inflammatory diseases, neurodegenerative diseases, and hypertension.
- Decreases ROS levels in NMDA- and Kainic acid-stimulated rat cerebellar granule cells.
- Enhances hypermotility in female NMRI mice.
- Potentiates the pressor effect of Noradrenaline in Reserpine-pretreated pithed cats.
- Enhances the anticonvulsant effect of Diphenylhydantoin in mice.
- Induces increased motor activity, rectal temperature, and elevated brain levels of 5-HT, NA, and dopamine in mice.
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