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Medchemexpress LLC NIC-0102 | 2806031-94-5 | C21H25BF2N2O4 | 1 ML
Supplier: Medchemexpress LLC HY15125210MM/1ML
NIC-0102 is an orally active proteasome inhibitor that specifically inhibits NLRP3 inflammatory vesicle activation. It demonstrates potent anti-inflammatory effects in a model of dextran sulfate sodium (DSS)-induced ulcerative colitis.
- Inhibits proteasome with a pIC50 of 7.55
- Specifically inhibits NLRP3 inflammatory vesicle activation
- Shows potent anti-inflammatory effects
- Inhibits production of pro-IL-1β
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