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Medchemexpress LLC Nicodicosapent | 1269181-69-2 | 99.8% | 449.63 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY1764050MG

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Nicodicosapent is a fatty acid niacin conjugate that inhibits the sterol regulatory element binding protein (SREBP), a key regulator of cholesterol metabolism proteins including PCSK9, HMG-CoA reductase, ATP citrate lyase, and NPC1L1. This product is for research use only.

  • Inhibitor of sterol regulatory element binding protein (SREBP)
  • Decreases mature SREBP-2 protein production in HepG2 cells
  • Synergistically inhibits secreted PCSK9
  • Significantly inhibits ApoB secretion in a dose-dependent manner
  • Reduces PCSK9 levels, LDL particles, and plasma triglycerides in ApoE*3-Leiden mice

Catalog No. 50-003-87039


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