Cayman Chemical nIdulafungIn 10mg

Supplier:  Cayman Chemical 2075310 MG

An FP receptor agonist and active metabolite of latanoprost selectively binds to the FP receptor (Ki 0 098 UM) over the EP1 EP2 EP3 and EP4 receptors (Kis 2 06 39 667 7 519 and 75 UM respectively) as well as the DP IP and TP receptors (Kis 20 90 and 60 UM respectively) induces phosphoinositide turnover in isolated human ciliary muscle and human trabecular meshwork cells mouse NIH3T3 fibroblasts and rat A7r5 vascular smooth muscle cells which all endogenously express FP receptors (EC50s 124 35 32 and 35 nM respectively) as well as HEK293 cells expressing human ocular FP receptors (EC50 45 7 nM) increases intracellular calcium levels in hEP1-5/293-AEQ17 cells expressing EP1 receptors in an aequorin-based calcium assay (EC50 119 nM) induces contraction of isolated cat iris sphincter smooth muscle (EC50 29 9 nM)

Catalog No. 50-298-3331