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Medchemexpress LLC Nifuroxazide (standard) | 965-52-6 | 10 G
Supplier: Medchemexpress LLC HYB143610G
Nifuroxazide is an orally active nitrofuran antibiotic that effectively inhibits STAT3, exhibiting potent anti-tumor and anti-metastasis activities.
- Effective inhibitor of STAT3.
- Exhibits potent anti-tumor and anti-metastasis activity.
- Inhibits STAT3 tyrosine phosphorylation in U266 cells.
- Causes dose-dependent loss of cell viability in U266 or INA6 cells.
- Inhibits tumor growth and weight in mice.
- Inhibits proliferation of Ki-67-positive cells and induces apoptosis.
- Inhibits expression of MMP-2, MMP-9, and p-Stat3 in A375 tumor tissues.
- Suppresses distant colonization of tumor cells in melanoma metastasis models by inhibiting MDSCs infiltration into the lung.
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