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Medchemexpress LLC Nigericin sodium salt | 28643-80-3 | MFCD00036825 | >=98.0% | 746.94 | C40H67NaO11 | 25 MG
SDP

Supplier:  Medchemexpress LLC HY10038125MG

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Nigericin sodium salt is an ionophore antibiotic derived from Streptomyces hygroscopicus that facilitates K+/H+ exchange across membranes and functions as an NLRP3 activator. It is used in research to lower intracellular pH, modulate signaling pathways, and study programmed cell death mechanisms in cancer models.

  • Acts as a K+/H+ ionophore and NLRP3 activator.
  • Used to decrease intracellular pH and modulate Wnt/β-catenin signaling.
  • Reported to induce pyroptosis via caspase-1/GSDMD in cancer studies.
  • Molecular formula C40H67NaO11; molecular weight 746.94 g/mol.
  • CAS number 28643-80-3.
  • High purity available (≥98% by TLC) for research applications.

Catalog No. 50-002-14292


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