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Medchemexpress LLC Ninerafaxstat | 2254741-41-6 | 99.1% | 415.48 | 100 MG
Supplier: Medchemexpress LLC HY139577100MG
Ninerafaxstat is a novel orally active cardiac mitochondrial drug engineered to restore myocardial energy homeostasis. It functions by competitively inhibiting 3-ketoacyl-CoA thiolase (3-KAT), which partially suppresses fatty acid oxidation and redirects cardiac energy metabolism from fatty acid oxidation to glucose oxidation. This mechanism regulates myocardial substrate utilization, leading to improved cardiac efficiency and making it suitable for cardiovascular disease research.
- Restores myocardial energy homeostasis
- Competitively inhibits 3-ketoacyl-CoA thiolase (3-KAT)
- Partially suppresses fatty acid oxidation
- Shifts cardiac energy metabolism to glucose oxidation
- Regulates myocardial substrate utilization
- Improves cardiac efficiency
- Useful for research on cardiovascular diseases
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