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Medchemexpress LLC Nirogacestat | 1290543-63-3 | C27H41F2N5O | 1 ML
SDP

Supplier:  Medchemexpress LLC HY1518510MM/1ML

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Nirogacestat (PF-3084014) is a reversible, orally bioavailable, noncompetitive, and selective γ-secretase inhibitor with an IC50 of 6.2 nM. It inhibits Notch signaling, which is a promising approach for research of Notch receptor-dependent cancers while minimizing gastrointestinal toxicity.

  • Reversible, orally bioavailable, noncompetitive, and selective γ-secretase inhibitor
  • Inhibits Notch signaling
  • Minimizes gastrointestinal toxicity
  • Potential for research of Notch receptor-dependent cancers

Catalog No. 50-003-74144


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