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Medchemexpress LLC Nirogacestat | 1290543-63-3 | C27H41F2N5O | 50 MG

Supplier: Medchemexpress LLC HY1518550MG
Nirogacestat is a reversible, orally bioavailable, noncompetitive, and selective γ-secretase inhibitor. With an IC50 of 6.2 nM, it inhibits Notch signaling, minimizing gastrointestinal toxicity, and presents a promising approach for research of Notch receptor-dependent cancers.
- Reversible, orally bioavailable, noncompetitive, and selective γ-secretase inhibitor.
- IC50 of 6.2 nM.
- Inhibits Notch signaling.
- Minimizes gastrointestinal toxicity.
- Promising approach for research of Notch receptor-dependent cancers.
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