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Medchemexpress LLC NITD-349 | 1473450-62-2 | 99.7% | 306.35 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY10958850MG

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NITD-349 is an MmpL3 inhibitor that shows highly potent anti-mycobacterial activity with MIC50 of 23 nM against virulent Mycobacterium tuberculosis H37Rv. It is for research use only.

  • Exhibits bactericidal activity against in vitro replicating Mycobacterium tuberculosis (Mtb)
  • Active against intramacrophage Mtb
  • Shows high permeability and moderate in vitro metabolic clearance in mouse and human hepatic microsomes
  • Demonstrated favorable oral pharmacokinetic (PK) properties in rodents and dogs
  • Efficacious in mouse models of both acute and chronic Mycobacterium tuberculosis infection

Catalog No. 50-003-45075


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