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Medchemexpress LLC Nitisinone | 104206-65-7 | 99.9% | 50 MG
SDP

Supplier:  Medchemexpress LLC HYB060750MG

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Nitisinone is an orally active, competitive, and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC50 of 173 nM. It promotes tyrosine accumulation in a dose-dependent manner and is used in studies of hereditary tyrosinemia type 1 (HT-1), a rare genetic disorder, and albinism.

  • Orally active, competitive, and reversible 4-HPPD inhibitor
  • Promotes tyrosine accumulation
  • Used in studies of hereditary tyrosinemia type 1 (HT-1) and albinism
  • Exhibits antiproliferative activity against various cell lines (HCT-116, HUVEC, L02, MC-38)
  • Increases pigmentation in irides and new hair growth in albinism mouse models

Catalog No. 50-004-05940


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