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Cusabio Technology LLC Human NACHT, LRR and PYD domains-containing protein 3 (NLRP3/C1orf7/CIAS1/NALP3/PYPAF1) ELISA kit
Supplier: Cusabio Technology LLC CSBE15885H
The human NLRP3 ELISA Kit allows for the in vitro quantitative determination of NLRP3 concentrations in serum, plasma, or tissue homogenates. This kit exclusively recognizes human NLRP3. NLRP3 inflammasome is a multi-protein complex containing a sensor NLRP3 protein, an adaptor apoptosis-associated speck-like protein (ASC), and the zymogen procaspase-1. It is a critical component of the innate immune system that mediates the activation of caspase-1 and the secretion of proinflammatory cytokines IL-1β/IL-18 in response to microbial infection and cellular damage. The NLRP3 inflammasome is involved in the modulation of numerous physiological and pathological processes, such as infections, tissue repair, autoimmune diseases, and cancer. Aberrant activation of the NLRP3 inflammasome has been linked with several inflammatory disorders, which include cryopyrin-associated periodic syndromes (CAPS), Alzheimer's disease, diabetes, and atherosclerosis. One kit contains 96 wells.
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