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Medchemexpress LLC Nms-873 | 1418013-75-8 | MFCD28009371 | >98% | 520.67 | C27H28N4O3S2 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY1571310MG

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NMS-873 is a potent, selective allosteric inhibitor of the VCP/p97 ATPase used in research to study protein homeostasis, ubiquitin-proteasome system dysfunction, and cell-cycle/DNA damage pathways. It exhibits strong biochemical inhibition (IC50 30 nM) and antiproliferative activity in cell lines at sub-micromolar concentrations.

  • Potent allosteric inhibition of VCP/p97 (IC50 30 nM).
  • Demonstrates antiproliferative activity in tumor cell lines (cellular IC50 ~0.08-2 μM).
  • Suitable for cell-based assays and biochemical studies of protein degradation and autophagy.
  • Provided as a solid with recommended storage conditions for powder and solutions.
  • Available in small-scale quantities (for example, 1 mg, 5 mg, 10 mg) for laboratory experiments.

Catalog No. 50-002-87832


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