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Apexbio Technology LLC Nocodazole 31430-18-9 50mg
Supplier: Apexbio Technology LLC A848750
Nocodazole (CAS 31430-18-9) is an anti-mitotic small molecule commonly utilized in biomedical research as a potent and reversible inhibitor of microtubule polymerization Its mechanism involves direct binding to -tubulin disrupting microtubule assembly and stability It exhibits inhibitory effects on various kinases associated with oncogenesis including Abl c-Kit BRAF and MEK and induces apoptosis in cancer cells In vitro exposure at high concentrations rapidly depolymerizes microtubules while lower concentrations primarily affect their dynamic instability Nocodazole serves as a valuable tool in studies probing microtubule dynamics intracellular trafficking cell cycle regulation and antitumor therapeutic evaluations
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