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Apexbio Technology LLC Norfloxacin 70458-96-7 10g
Supplier: Apexbio Technology LLC B180110000
Norfloxacin (70458-96-7) is a small-molecule inhibitor targeting bacterial DNA gyrase It is designed to inhibit DNA gyrase thereby interfering with bacterial DNA replication and transcription Norfloxacin exerts its biological activity primarily through inhibition of topoisomerase activity by binding to bacterial DNA gyrase disrupting DNA supercoiling and strand separation Norfloxacin demonstrates broad-spectrum antibacterial inhibition with reported IC50 values ranging from approximately 0 1 to 10 M depending on bacterial species and assay conditions Based on these pharmacological properties norfloxacin holds research potential in studies of bacterial DNA replication mechanisms antimicrobial susceptibility assays and resistance analyses
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