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Medchemexpress LLC (±)-Nornicotine | 5746-86-1 | 148.20 | 50 MG
Supplier: Medchemexpress LLC HYW00211250MG
(±)-Nornicotine is a major metabolite of Nicotine that acts as a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. This compound disrupts β-catenin and ZO-1, and induces F-actin depolymerization. It supports self-administration behavior and can be utilized in research concerning atherosclerosis, Alzheimer's disease, and schizophrenia.
- Acts as a partial nAChRs agonist
- Activates receptor subtypes containing α7 and α6 subunits
- Disrupts β-catenin and ZO-1
- Induces F-actin depolymerization
- Supports self-administration behavior
- Suitable for research concerning atherosclerosis, Alzheimer's disease, and schizophrenia
- Promotes cell migration and disrupts adherens/tight junctions in vitro
- Maintains self-administration behavior in vivo
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