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Medchemexpress LLC Notch 1 | 2408730-51-6 | 95.4% | 1500.72 | 5 MG
SDP

Supplier:  Medchemexpress LLC HYP19855MG

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Notch 1 (Notch homolog 1, translocation-associated) encodes a member of the NOTCH family of proteins. These Type I transmembrane proteins have an extracellular domain with multiple epidermal growth factor-like (EGF) repeats and an intracellular domain with multiple different domain types.

  • Promotes mouse luminal prostate cell survival and proliferation by activating the prosurvival NF-κB pathway.
  • Down-regulation reduces in vitro invasion and cell growth in human prostate cancer cell lines.

Catalog No. 50-004-23516


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