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Medchemexpress LLC NPS-2143 hydrochloride | 324523-20-8 | MFCD16038896 | 100.0% | 445.38 g·mol⁻¹ | C24H26Cl2N2O2 | 10 MG
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Supplier:  Medchemexpress LLC HY1017110MG

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NPS-2143 hydrochloride is an orally active calcilytic agent and a selective, potent antagonist of the calcium-sensing receptor (CaSR). It inhibits CaSR-mediated increases in cytoplasmic Ca2+ (reported IC50 ≈ 43 nM) and is used as a research reagent for studies of CaSR signaling, pharmacology, and related cellular assays.

  • Selective CaSR antagonist with reported IC50 ≈ 43 nM.
  • High purity (≈99.98%).
  • Solid, white to off-white powder suitable for laboratory use.
  • Molecular weight 445.38 g·mol⁻¹; molecular formula C24H26Cl2N2O2.
  • Recommended storage: 4°C sealed; in solvent -80°C (6 months), -20°C (1 month).
  • Available in small research pack sizes (for example, 10 mg).

Catalog No. 50-002-46997


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