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Medchemexpress LLC Nrf2 activator-2 | 2770448-53-6 | 99.2% | C20H17BrO3 | 25 MG
Supplier: Medchemexpress LLC 25MGHY145879
Nrf2 activator-2 (compound O15), an Osthole derivative, is a potent Nrf2 agonist with an EC50 of 2.9 μM in 293 T cells. This compound effectively inhibits the interaction between Keap1 and Nrf2, thereby activating Nrf2 and leading to a marked decrease in the level of ubiquitinated Nrf2 in cells.
- Potent Nrf2 agonist.
- Effectively inhibits Keap1-Nrf2 interaction.
- Activates Nrf2 signaling pathway.
- Decreases ubiquitinated Nrf2 levels.
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