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Medchemexpress LLC NS3623 | 343630-41-1 | 99.0% | 427.18 | 100 MG
Supplier: Medchemexpress LLC HY10858610MM/1ML
NS3623 is an activator of human ether-a-go-go-related gene (hERG1/KV11.1) potassium channels. It activates the IKr and Ito currents and exhibits antiarrhythmic effects. It also has a dual mode of action, acting as an inhibitor of hERG1 channels. NS3623 is suitable for laboratory research and studies related to cardiac electrophysiology.
- Increases IKr tail currents in isolated canine cardiomyocytes
- Shortens corrected QT interval in anesthetized guinea pigs
- Improves repolarization reserve
- Normalizes ventricular action potentials
- Exhibits antiarrhythmic effects
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