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Medchemexpress LLC NS3694 | 426834-38-0 | 99.9% | 358.70 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY10835650MG

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NS3694 is a diarylurea compound that acts as an apoptosome inhibitor. It inhibits apoptosome formation and caspase activation.

  • Inhibits apoptosome formation and caspase activation.
  • Specifically suppresses cytochrome C-induced formation of apoptosome complex and caspase-9 activation, thereby inhibiting mitochondria-mediated apoptosis.
  • Inhibits the formation of apoptosome Apaf-1 by blocking the activation of initiator caspase-9.
  • Inhibits caspase 9, 3, and 7 processing, DFF45/ICAD and PARP cleavage, and DEVDase activity in a dose-dependent manner.
  • Inhibits TNF-induced effector caspase activation and apoptosis in MCF-casp3 cells.

Catalog No. 50-003-44296


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