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Medchemexpress LLC Nsc 66811 | 6964-62-1 | 98.12% | 340.42 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY1496710MM/1ML

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NSC 66811 is an MDM2-p53 inhibitor, with a Ki of 120 nM for binding to MDM2, suitable for research use. It has a molecular weight of 340.42 and a purity of 98.12%. This compound demonstrates the following biological activities:

  • Dose-dependently induces the accumulation of p53, MDM2, and p21cip1/waf proteins due to the functional activation of p53.
  • Effective in HCT-116 human colon cancer cell line with wild-type p53.
  • Has no effect on the levels of p53, MDM2, and p21cip1/waf protein in the isogenic HCT-116 p53-/- cell line.

Catalog No. 50-003-60100


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