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Medchemexpress LLC NTRC 0066-0 | 1817791-73-3 | 99.01% | 565.71 | 5 MG
Supplier: Medchemexpress LLC 5MGHY100024
NTRC 0066-0 is a selective threonine tyrosine kinase (TTK) inhibitor, demonstrating potent anti-proliferative activity against diverse cancer cell lines. With an IC50 of 0.9 nM, it is utilized in cancer research, exhibiting low selectivity entropy and a prolonged target residence time on TTK.
- Selective threonine tyrosine kinase (TTK) inhibitor (IC50=0.9 nM).
- Used for cancer research.
- Exhibits low selectivity entropy.
- Relatively long target residence time on TTK.
- Inhibits proliferation of diverse cancer cell lines with potency similar to classic chemotherapeutic agents.
- Demonstrates subnanomolar potency in a TTK enzyme assay.
- Inhibits tumor growth in a mouse xenograft model of human triple-negative breast cancer (TNBC).
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