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Medchemexpress LLC NUCC-390 dihydrochloride | 2749281-71-6 | 98.2% | 468.46 | 100 MG
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Supplier:  Medchemexpress LLC HY111793A100MG

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NUCC-390 dihydrochloride is a novel and selective small-molecule CXCR4 receptor agonist. It induces internalization of CXCR4 receptors and acts in an opposite way to AMD3100. NUCC-390 dihydrochloride promotes nerve recovery of function after neurodegeneration in vivo.

  • Novel and selective small-molecule CXCR4 receptor agonist.
  • Induces internalization of CXCR4 receptors.
  • Acts in an opposite way of AMD3100.
  • Promotes nerve recovery of function after neurodegeneration in vivo.
  • Produces strong (Ca)i response (at 10 μM).
  • Stimulates signaling activity downstream of CXCR4 receptors.
  • Boosts axonal growth in cultured cerebellar granule neurons (CGNs) via CXCR4.
  • Contributes to the functional and anatomical recovery of the neuromuscular junction (NMJ) following acute nerve terminal damage in vivo.

Catalog No. 50-004-39257


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