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Medchemexpress LLC Nx-1607 | 2573775-59-2 | 99.9% | 537.62 | C30H34F3N5O | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1414325MG

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NX-1607 is a first-in-class, orally bioavailable small-molecule inhibitor of the E3 ubiquitin ligase Cbl-b. It exhibits sub-nanomolar potency (IC50 < 1 nM) and is used in preclinical and clinical immuno-oncology research to enhance T-cell activation, reduce exhaustion, and increase antigen recall and cytokine production. Supplied for laboratory research use only.

  • Potent sub-nanomolar inhibitory activity against Cbl-b.
  • Enhances T-cell activation and antigen recall.
  • Reduces T-cell exhaustion and increases cytokine production.
  • Orally bioavailable small molecule suitable for in vivo studies.
  • High purity solid with white to off-white appearance.
  • Stable when stored sealed; follow recommended storage conditions.
  • Supplied in small-scale packaging for research applications.

Catalog No. 50-002-23286


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