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Selleck Chemical LLC NX-1607 E1957-100MG
Supplier: Selleck Chemical LLC E1957100MG
NX-1607 (Cbl-b-IN-3) is an oral inhibitor of Casitas B-lineage lymphoma proto-oncogene B (CBL-B) which is an E3 ubiquitin ligase and a key regulator of T NK and dendritic cell activation and suppresses their anti-tumor functions NX-1607 enhances antigen recall reduces T cell exhaustion and increases cytokine production in response to T cell receptor stimulation thereby counteracting suppressive signals from the tumor microenvironment
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