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Medchemexpress LLC O-Phospho-L-serine | 407-41-0 | C3H8NO6P | 25 MG
Supplier: Medchemexpress LLC 25MGHY15129R
O-Phospho-L-serine is an endogenous metabolite that acts as the immediate precursor to L-cystein in the serine synthesis pathway. It functions as an agonist at group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8), while also serving as a weak antagonist for mGluR1 and a potent antagonist for mGluR2. This product is intended for research use only.
- Weakly binds to mGluR1 and antagonizes the effects of l-glutamate
- Activates group III receptors (mGluR4, mGluR6, mGluR7, and mGluR8)
- Enhances intracellular calcium responses in mGluR4 transfected cells
- Inhibits l-glutamate mediated mGluR1 response
- Potently inhibits mGluR2 activation
- Induces membrane potential changes in HEK/TRPC4 cells transfected with mGluR4 or mGluR6, mediating TRPC4β activation
- Inhibits Müller glia proliferation in light-damaged retinas
- Inhibits cone cell regeneration in light-damaged retinas
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