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Medchemexpress LLC OARV-771 | 2683008-37-7 | 98.77% | C49H59ClN8O8S2 | 1 ML
Supplier: Medchemexpress LLC HY14526410MM/1ML
OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. It demonstrates an antiproliferative effect with an EC50 value of 4 nM in MV4;11 cells. It is for research use only.
- Shows DC50s of 6, 1, and 4 nM for Brd4, Brd2 and Brd3, respectively
- Demonstrates an antiproliferative effect with an EC50 value of 4 nM in MV4;11 cells
- Targets BRD4, BRD2, BRD3, and VHL
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