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Medchemexpress LLC Ogerin | 1309198-71-7 | 99.9% | 307.35 | 1 ML
Supplier: Medchemexpress LLC HY11027910MM/1ML
Ogerin is a chemical probe and a selective GPR68 positive allosteric modulator (PAM) with a pEC50 of 6.83. It also has a moderate antagonistic effect on A2A (Ki=220 nM). Ogerin inhibits the fear conditioning reflex in mice and prevents TGF-β-induced myofibroblast differentiation of fibroblasts from multiple organ systems. It is suitable for studies related to fibrotic diseases and neurological disorders.
- Selective GPR68 positive allosteric modulator (PAM).
- Moderate antagonistic effect on A2A (Ki=220 nM).
- Inhibits fear conditioning reflex in mice.
- Prevents TGF-β-induced myofibroblast differentiation of fibroblasts.
- Suitable for studies related to fibrotic diseases.
- Suitable for studies related to neurological disorders.
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