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Medchemexpress LLC Ogerin | 1309198-71-7 | >99.9% | 307.35 | 50 MG
Supplier: Medchemexpress LLC HY11027950MG
Ogerin is a chemical probe that acts as a selective GPR68 positive allosteric modulator (PAM) with a pEC50 of 6.83. It also exhibits a moderate antagonistic effect on A2A with a Ki of 220 nM. This compound has been shown to inhibit the fear conditioning reflex in mice and to suppress TGF-β-induced myofibroblast differentiation in fibroblasts from various organ systems. It is primarily utilized in research contexts for the study of fibrotic diseases and neurological disorders.
- Selective GPR68 positive allosteric modulator (PAM)
- Inhibits fear conditioning reflex in mice
- Inhibits TGF-β-induced myofibroblast differentiation
- Can be used in studies of fibrotic diseases and neurological disorders
- For research use only
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